Masters Group Granted Global Distribution Rights to New Break-Through Melatonin Based Sleep Aid

Masters Group Granted Global Distribution Rights to New Break-Through Melatonin Based Sleep Aid

June 05, 2007

    MIAMI, June 5 /Xinhua-PRNewswire/ -- The Masters Group
is pleased to announce that it has been granted exclusive
worldwide distribution rights to Mellow-Tone(TM). 
Mellow-Tone(TM) is a break-through premium dietary
supplement made from pharmaceutical grade Melatonin.  It is
intended for use by persons suffering from occasional
insomnia or sleep difficulty caused by restlessness,
nervous tension, anxiety, mild to moderate mood changes,
and jet lag as well as daytime drowsiness caused by
occasional sleeplessness.

    Sleep researchers estimate that occasional insomnia
affects over 37 million people in the U.S. and
conservatively place the number of people suffering from
the condition worldwide at well over 100 million people. 
The prevalence of this sleep disorder globally is expected
to increase dramatically over the next few years.  The
current market is valued at USD $4.3 billion but is
forecast to increase by 158% to USD $11 billion by 2012.

    Sleep deprivation results in a wide variety of negative
health and economic consequences.  In the short term, lack
of sleep can impair our ability to perform routine daily
activities.  It affects us both mentally and physically. 
These effects include fatigue, irritability, careless
mistakes, difficulty concentrating, slower reaction times,
and increased stress.  Prolonged sleep deprivation can also
lead to very serious long-term health problems including an
increased risk of hypertension, diabetes, obesity,
depression, heart attack, and stroke.  The economic impact
of sleep deprivation on a societal basis is staggering. 
Estimates of the direct and indirect financial costs of
sleeplessness are in the hundreds of billion of dollars
annually.  Direct costs are those incurred for the actual
medical treatment of sleep disorders, and indirect costs
are those that are linked to peoples' sleeplessness such as
reduced productivity and property damage.

    There is hope in addressing this looming public health
crisis.  Clinical studies show that the hormone Melatonin
administered as a dietary supplement is effective in
increasing the overall quantity and quality of one's sleep.
 Melatonin is an essential physiological agent that is
produced in the brain by the pineal gland to regulate
Circadian rhythms as well as other bodily systems. 
Circadian rhythms are regular changes in mental and
physical characteristics that take place naturally in the
course of a day.  Among these natural daily rhythms is an
increase in the level of Melatonin at night, making people
feel drowsy.  Recent research has linked numerous health
problems to dysfunctions of Circadian rhythms including
various sleep disorders.

    In a review of 28 clinical trials involving Melatonin
on behalf of the U.S. Department of Health and Human
Services, researchers found that the results were
clinically and statistically significant based on sleep
efficiency criteria, which is a comparison of the amount of
time participants spent asleep to the total time spent in
bed.  In another systematic analysis of 33 clinical trials,
researchers found that the use of Melatonin resulted in a
clinically and statistically significant reduction in the
onset of sleep.  In addition, study participants given
Melatonin spent more time in REM sleep, woke up less often,
and reported improved sleep quality compared with those
study participants given a placebo.  The results of the
clinical studies reviewed clearly indicate that Melatonin
taken as a dietary supplement is effective in improving the
overall quality and quantity of sleep.

    Mellow-Tone(TM) offers a unique sublingual delivery
system in a strip placed on the tongue.  It is doctor
formulated and doctor recommended and is available through
physician offices and other healthcare providers. 
Mellow-Tone(TM) is manufactured in the United States by KRS
Global Biotechnology, Inc.

    The Masters Group is a premier customer-focused,
full-service wholesale distribution company that ethically
markets and distributes prescription and OTC
pharmaceuticals, medical supplies, and equipment to the
global healthcare community.  The Masters Group has offices
in the United States, England, and El Salvador.  We proudly
serve the local and national medical needs of clients
located on nearly every continent, focusing specifically on
niche markets in the United States, Latin America, the
Caribbean, Europe, the Middle East, Africa, and Asia.  For
more information about The Masters Group, kindly visit us
at http://www.masters-usa.com .


    For more information, please contact:

     Ms. Shawn Resch
     C.E.O. of Masters Medical Inc.
     Tel:   [phone]
     Fax:   [phone]
     Email: [e-mail]
     Web:   http://www.masters-usa.com